Twitter’s best feature is something they try to make as obscure as possible: lists.
You can group together certain users and see a timeline of just their tweets and no ads. These lists can even be private, so you don’t need to signal with who you follow. Problem is, it’s hidden behind at least five clicks and it’s painful to use. So instead I made a web app to make managing them Drag-and-Drop Simple™.
Give it a go at ClusterLists.com.
I use it to separate out my actual friends from all the prolific tech bloggers and news sites. I can look at my friends list and not miss anything they tweet (if I wanted).